Summary
This support unit manages the animal facility and, through technical support using reproductive engineering technologies, carries out the generation, preservation, and management of biological resources.
At IMS, we strive to elucidate life phenomena and conduct research using laboratory animals such as mice to uncover the mechanisms underlying human diseases and to establish novel therapeutic strategies based on these findings. The animal facility is capable of handling for up to 60,000 mice and maintains Specific Pathogen-Free (SPF) environment. In addition, we maintain vinyl isolator systems that enable the maintenance of germ-free mice for microbiota and mucosal immunology research and severely immunodeficient mice for studies such as humanized mice. We also maintain and manage animal rooms for infectious disease research.
At IMS, we strive to elucidate life phenomena and conduct research using laboratory animals such as mice to uncover the mechanisms underlying human diseases and to establish novel therapeutic strategies based on these findings. The animal facility is capable of handling for up to 60,000 mice and maintains Specific Pathogen-Free (SPF) environment. In addition, we maintain vinyl isolator systems that enable the maintenance of germ-free mice for microbiota and mucosal immunology research and severely immunodeficient mice for studies such as humanized mice. We also maintain and manage animal rooms for infectious disease research.
Haruhiko Koseki M.D., Ph.D.
Activity
- Support Services
- ● Comprehensive management of animal facilities
- ● Rederivation of mice using in vitro fertilization and embryo transfer
- ● Production of cryopreserved mouse embryos and sperm
- ● Generation of genetically modified mice
- - Generation of transgenic mice by microinjection
- - Generation of genome-edited mice using CRISPR-Cas9
- - Generation of gene-targeted mice using ES cells
- ● Generation of germ-free mice
- ● Establishment of mouse ES cell lines
Resources and Facilities
Clean rack for
Vinyl isolator for
Micromanipulator-equipped
SPF mice
Germ-free mice
microscope for microinjection
Support for external users
・If you are not affiliated with RIKEN and are interested in commissioned research, Please refer to the RIKEN Research and Technical Cooperation page.