High-quality, high-yield protein production is a fundamental requirement for structural biology, functional analysis, and drug discovery research. Although significant progress in expression and purification technologies has enabled the handling of a wide variety of biomolecules, sample preparation―including expression optimization, solubilization, and stabilization―has long been a critical factor determining research success. This remains a major challenge, particularly for membrane proteins, large macromolecular complexes, and targets containing intrinsically disordered regions.
　Protein Production Support Unit provides multiple expression platforms, including an E. coli cell-free synthesis system, expression system in E. coli, yeast, insect cells, and mammalian cells. We systematically evaluate and select the most suitable system according to the biochemical and biophysical properties of each target protein. From the design of purification strategies utilizing fast liquid chromatography systems to quality assessment and seamless integration into functional and structural analyses, our research scientists and technical staffs provide comprehensive, end-to-end support.